Inhibition of murine chronic graft-versus-host disease by the chloroform extract of Tripterygium wilfordii Hook f
K Asano, Y Yu, T Kasahara, T Hisamitsu - Transplant Immunology, 1997 - Elsevier
The effects of chloroform extract of Tripterygium Wilfordii Hook f (TWH extract) on chronic
graft-versus-host disease (GVHD) were examined in a murine experimental model. Chronic
GVHD was induced by intravenous transfer of parental DBA/2 spleen cells into unirradiated
(C57BL/6× DBA/2) F1 recipient mice. The effects of TWH extract on GVHD were assessed by
measuring both the degree of splenomegaly and the total serum IgE levels 3 weeks after the
cell transfer. Subcutaneous administration of TWH extract once a day for 3 weeks …
graft-versus-host disease (GVHD) were examined in a murine experimental model. Chronic
GVHD was induced by intravenous transfer of parental DBA/2 spleen cells into unirradiated
(C57BL/6× DBA/2) F1 recipient mice. The effects of TWH extract on GVHD were assessed by
measuring both the degree of splenomegaly and the total serum IgE levels 3 weeks after the
cell transfer. Subcutaneous administration of TWH extract once a day for 3 weeks …
