Cardiovascular disease and cancer: evidence for shared disease pathways and pharmacologic prevention

F Masoudkabir, N Sarrafzadegan, C Gotay… - Atherosclerosis, 2017 - Elsevier
Cardiovascular disease (CVD) and cancer are leading causes of mortality and morbidity
worldwide. Strategies to improve their treatment and prevention are global priorities and
major focus of World Health Organization's joint prevention programs. Emerging evidence
suggests that modifiable risk factors including diet, sedentary lifestyle, obesity and tobacco
use are central to the pathogenesis of both diseases and are reflected in common genetic,
cellular, and signaling mechanisms. Understanding this important biological overlap is …