[HTML][HTML] Influence of test technique on sensitization status of patients on the kidney transplant waiting list

P Gombos, G Opelz, S Scherer, C Morath… - American Journal of …, 2013 - Elsevier
The exquisitely sensitive single antigen bead (SAB) technique was shown to detect human
leukocyte antigen (HLA) antibodies in sera of healthy male blood donors. Such false
reactions can have an impact on critical decisions, especially with respect to the
determination of unacceptable HLA-antigen mismatches in patients awaiting a kidney
transplant. We tested pretransplant sera of 534 patients on the kidney waiting list using
complement-dependent cytotoxicity (CDC), enzyme-linked immunosorbent assay (ELISA) …